Nanotechnology in drug delivery system

  • Alamanda Lokesh Priyadarshini Institute of Pharmaceutical Education and Research, 5th Mile, Pulladigunta, Guntur-522017.Andhra Pradesh, India.
  • Potu Harikrishna Priyadarshini Institute of Pharmaceutical Education and Research, 5th Mile, Pulladigunta, Guntur-522017.Andhra Pradesh, India.
  • Chava Lakshmi Narayanamma Priyadarshini Institute of Pharmaceutical Education and Research, 5th Mile, Pulladigunta, Guntur-522017.Andhra Pradesh, India.
  • Chandu Babu Rao Priyadarshini Institute of Pharmaceutical Education and Research, 5th Mile, Pulladigunta, Guntur-522017.Andhra Pradesh, India.

Abstract

A definition of nanotechnology is the science of designing, creating, characterizing, and using materials and technologies whose smallest functional organization in at least one dimension is on the nanoscale scale. Because of its high selectivity towards the target region, nanotechnology application is highly significant in the field of drug delivery. Drugs can also be shielded against deterioration by delivery methods based on nanotechnology. These characteristics have the potential to lower treatment costs, improve treatment outcomes, and minimize the number of doses needed. With the help of nanotechnology, we can also stop diseases before they even harm our bodies, such as with DNA vaccines. The creation of biodegradable polymeric nanoparticles has been a brilliant idea in the field of nanoparticles since they can transport medications. Over the past ten years, the research and supply of drugs has grown to be one of the manufacturing industries with the highest capital investments, demands, and growth. The issue of conventional drugs is reviewed, along with the importance of nanoparticles in medication delivery and their potential for toxicity. Differently synthesised nanoparticles have demonstrated improved therapeutic efficacy, stabilized drug delivery, and demonstrated the ability to selectively target cells and release drug within them under regulated conditions.

Keywords: Nanotechnology, health care, side effects, revolutionizing concentration

References

1. Emerich DF, Thanos CG. Nanotechnology and medicine. Expert opinion on biological therapy. 2003 Jul 1; 3(4):655-63.
2. Sahoo SK, Labhasetwar V. Nanotech approaches to drug delivery and imaging. Drug discovery today. 2003 Dec 15; 8(24):1112-20.
3. Williams D. Nanotechnology: a new look. Medical device technology. 2004 Oct 1; 15(8):9-10.
4. Cheng MM, Cuda G, Bunimovich YL, Gaspari M, Heath JR, Hill HD, Mirkin CA, Nijdam AJ, Terracciano R, Thundat T, Ferrari M. Nanotechnologies for biomolecular detection and medical diagnostics. Current opinion in chemical biology. 2006 Feb 1; 10(1):11-9.
5. Matsuda M, Hunt G. Nanotechnology and public health. Nihon Koshu Eisei Zasshi (JAPANESE JOURNAL OF PUBLIC HEALTH). 2005; 52(11):923-7.
6. Rani TT, Brahmaiah B, Revathi B, Nama S, Baburao C. TARGETING OF ANTI CANCER DRUGS THROUGH NANOPARTICLES.
7. Amulya A, Sirisha V, Rao CB, Chennam JV. CURRENT TRENDS ON ROLE OF NANO PARTICLES ON PULMONARY DISEASES. International Journal of Research in Pharmacy and Chemistry. 2012; 2(3):685-703.
8. Yoshikawa T, Tsutsumi Y, Nakagawa S. Development of nanomedicine using intracellular DDS. Nihon rinsho. Japanese Journal of Clinical Medicine. 2006 Feb 1; 64(2):247-52.
9. Moghimi SM, Hunter AC, Murray JC. Nanomedicine: current status and future prospects. The FASEB journal. 2005 Mar; 19(3):311-30.
10. Freitas Jr RA. The future of nanofabrication and molecular scale devices in nanomedicine. InFuture of Health Technology 2002 (pp. 45-59). IOS Press.
11. Singh BG, Baburao C, Pispati V, Pathipati H, Muthy N, Prassana SR, Rathode BG. Carbon nanotubes. A novel drug delivery system. International Journal of Research in Pharmacy and Chemistry. 2012; 2(2):523-32.
12. Vasir JK, Reddy MK, Labhasetwar VD. Nanosystems in drug targeting: opportunities and challenges. Current Nanoscience. 2005 Jan 1; 1(1):47-64.
13. Matsumura Y, Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer research. 1986 Dec 1; 46(12_Part_1):6387-92.
14. Pardridge WM. Vector-mediated drug delivery to the brain. Advanced drug delivery reviews. 1999 Apr 5; 36(2-3):299-321.
15. Anderson A, Allan S, Petersen A, Wilkinson C. The framing of nanotechnologies in the British newspaper press. Science communication. 2005 Dec; 27(2):200-20.
16. Ajayan PM, Iijima S, Ichihashi T. Electron-energy-loss spectroscopy of carbon nanometer-size tubes. Physical Review B. 1993 Mar 15; 47(11):6859.
17. Hughes GA. Nanostructure-mediated drug delivery. Nanomedicine: nanotechnology, biology and medicine. 2005 Mar 1; 1(1):22-30.
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Alamanda, L., Potu, H., Chava, L. N., & Chandu, B. R. (2024). Nanotechnology in drug delivery system. Journal of Integral Sciences, 7(1), 9-15. Retrieved from https://jisciences.com/index.php/journal/article/view/79
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Volume 7, Issue 1, 2024
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Review Article(s)
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