https://jisciences.com/index.php/journal/issue/feed 2024-11-11T01:57:05-05:00 Editor in Chief editor@jisciences.com Open Journal Systems <p>Journal of Integral Sciences(JIS) is an international, single blind peer-reviewed, open access journal that publish quarterly every year with high-quality papers in the fields of science and technology. These fields include all aspect of: Basic and applied Science (Biology, Molecular biology, Biotechnology, Chemistry, Physics, Biophysics, Geology, Astronomy, Mathematics, Statistics), Pharmaceutical Sciences, Engineering and Technology, Medicine, Dentistry, Veterinary medicine, Agricultural Sciences.</p> https://jisciences.com/index.php/journal/article/view/92 2024-11-11T01:57:05-05:00 Sanket J Soni sanket45.com@gmail.com Ankitkumar N Patel sanket45.com@gmail.com

<p>The pharmaceutical industry is undergoing a significant transformation driven by the integration of digital technologies, collectively known as Industry 4.0. This shift is redefining how drugs are developed, manufactured, and distributed. Key technologies such as the Internet of Things (IoT), Artificial Intelligence (AI), and big data analytics are at the forefront of this change, enabling smart manufacturing, real-time process optimization, and enhanced supply chain management. IoT facilitates the creation of interconnected production environments where sensors and devices continuously monitor critical parameters, ensuring optimal conditions and predictive maintenance. AI accelerates drug discovery through predictive modeling, automates quality control processes, and employs predictive analytics to enhance maintenance and process improvement. Big data empowers data-driven decision-making, ensures regulatory compliance through comprehensive analysis, and supports the shift toward personalized medicine by enabling customized drug production. Despite the significant benefits, the adoption of these technologies poses challenges, including integration with existing systems, data security concerns, and navigating a complex regulatory landscape. This review explores these technologies' impact on pharmaceutical manufacturing, highlighting successful case studies and best practices. Additionally, it discusses the future directions, including the move towards fully autonomous systems and the importance of collaboration between tech companies, manufacturers, and regulators to drive innovation and ensure compliance. The continued evolution of digital technologies in pharma manufacturing promises to enhance efficiency, reduce costs, and deliver more personalized treatments.</p>

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