DESIGN AND OPTIMIZATION OF AIR SUSPENSION MICROENCAPSULATION PROCESS

Jameela Shaik

Shaik. Jameela Priyadarshini Institute of Pharmaceutical Education and Research, 5TH Mile, Pulladigunta, Guntur-522017, Andhra Pradesh, India.

Abstract

Microencapsulation is a versatile and well-established technology used to entrap solid, liquid, or gaseous core materials within a protective coating to enhance stability, control release, and improve handling properties. The analyzed articles collectively highlight the fundamental principles, materials, techniques, and applications of microencapsulation across pharmaceutical, food, agricultural, textile, and construction industries. Various core and coating materials, including polymers, proteins, and lipids, are discussed with emphasis on their compatibility, biodegradability, and release characteristics. The articles also address microcapsule morphology, release mechanisms, and factors influencing encapsulation efficiency. Despite its advantages, challenges such as high production costs, scalability issues, and non-uniform particle size are noted. Overall, the reviewed literature demonstrates that microencapsulation is a critical enabling technology with significant potential for innovation, especially when optimized materials and methods are selected to meet specific application requirements.

Keywords: Release mechanisms, Microspheres, Controlled drug release, Microcapsules

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