Vitamin D Metabolism of Lipids

Sailaja Jallepalli

Jallepalli Sailaja Priyadarshini Institute of pharmaceutical Education and Research, 5th Mile, Pulladigunta, Guntur -522017, Andhra Pradesh, India.

Abstract

Though its historical significance in maintaining bone mineral homeostasis is widely recognized, new research indicates that vitamin D is also important for metabolic regulation. Using MS imaging, this study looked into potential connections between vitamin D deficiency [VDD] and disruptions in the metabolism of bioactive lipids. Across the world, vitamin D insufficiency is a prevalent health issue. Studies have started looking into its extra-skeletal benefits, or how it might prevent metabolic illnesses including obesity, hyperlipidemia, and diabetes mellitus, in addition to its well-known skeletal properties. These adverse metabolic effects of vitamin D deprivation have been studied, along with the underlying mechanisms. According to available data, a vitamin D shortage may affect the functioning of the pancreatic β-cell, which could lead to a compromise in the secretion of insulin. Furthermore, a lack of vitamin D may worsen oxidative stress, apoptosis, and inflammation in the pancreas and other organs, all of which contribute to insulin resistance. All of these will be involved in the disruption of glucose homeostasis. In order to determine how vitamin D may be used to prevent and treat metabolic illnesses, this review outlines the effects of vitamin D that have been documented on metabolism.on PCOS treatment using herbal remedies.

Keywords: Abdominal obesity, metabolic disorders, vitamin D supplementation, vitamin D intake

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