Congenital adrenal hyperplasia: an old concept with new perspective

  • V Siva Ganesh Department of Pharmacology, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, BG Nagar, Mandya-571448, Karnataka, India
  • G Venkata Nagaraju Department of Pharmacy Practice, School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India

Abstract

Congenital adrenal hyperplasia (CAH) incorporates a social occasion of autosomal uninvolved issues achieved by complete or partial distortions in one of a handful of the steroidogenic synthetic compounds related with the mix of cortisol from cholesterol in the adrenal organs. Around 1 in each 14,000 births and may cause questionable genitalia in female youngsters. By and by, CYP21A2 genotyping is seen as a significant enhancement to biochemical assessments in the finish of 21-hydroxylase need. In this study, we focus on sub-nuclear innate arrangements of 21-hydroxylase inadequacy, playing out a wide investigation of all clinical pathogenic varieties changing the whole progression of the CYP21A2 quality.

Keywords: CYP21A2, 21 hydroxylase, genital abnormaity, Adrenal steroidogenesis, classical and Non-classical congenital adrenal hyperplasia

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How to Cite
V, S. G., & G, V. N. (2021). Congenital adrenal hyperplasia: an old concept with new perspective. Journal of Integral Sciences, 4(1), 1-12. Retrieved from https://jisciences.com/index.php/journal/article/view/35
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