Journal of Integral Sciences <p>Journal of Integral Sciences(JIS) is an international, single blind peer-reviewed, open access journal that publish quarterly every year with high-quality papers in the fields of science and technology. These fields include all aspect of: Basic and applied Science (Biology, Molecular biology, Biotechnology, Chemistry, Physics, Biophysics, Geology, Astronomy, Mathematics, Statistics), Pharmaceutical Sciences, Engineering and Technology, Medicine, Dentistry, Veterinary medicine, Agricultural Sciences.</p> Journal of Integral Sciences en-US Journal of Integral Sciences 2581-5679 Anti-diabetic activity of Sida Cordifolia <p>Diabetes mellitus (DM) is one of the major diseases affecting the quality life of population around the world. There is no complete medication that controls the DM and its complications, in fact maintaining good health conditions. The traditional medicine which is principally based on medicinal plants (MPs) provides treatment for different diseases including DM and its complications. Many reports provide the evidence that different MPs possess anti-diabetic activity (ADA) and still many TMs are unexplored about their ADA. So, the current study aimed to evaluate the ADA of <em>Sidacordifolia</em>&nbsp;on Alloxan-induced diabetic mellitus in WISTAR albino rats. The phytochemical analysis of the extracts of <em>S. cordifolia</em>reveals the presences of different phytochemical components like sterols, terpenoids, alkaloids, flavanoids etc. The ethanolic and aqueous extracts showed dose dependent anti-diabetic activity as standard drug Glibenclamide. The extracts significantly controlled the blood glucose level, body weight loss and alteration in different lipid metabolic enzymes. The result of the present study provides the scientific confirmation to the traditional usage of <em>S. cordifolia</em>and more research is going on to assess different pharmacological activities and isolation of bioactive molecules from it<em>.</em></p> Narasimha Rao Y Naveen Babu K Srikanth M Copyright (c) 2020-04-01 2020-04-01 1 7