Study on Nootropic activity of Aegle marmelos L fruits

  • Kiran M Department of Pharmaceutical Chemistry, AU College of Pharmaceutical Sciences, Andhra University, India-530003
  • Viswanadha Murty NVSM Department of Pharmaceutical Chemistry, AU College of Pharmaceutical Sciences, Andhra University, India-530003.
  • Girija Sastry V Department of Pharmaceutical Chemistry, AU College of Pharmaceutical Sciences, Andhra University, India-530003.

Abstract

The present study carried out to evaluate the nootroptic protective effect of Aegle marmelos. Fresh A. marmelos fruits were used for methanolic extract preparation and used for the nootroptic protective activity on scopalamine induced amnesia in rats . The spatial memory was assessed by Morris water maze, and biomarker enzyme levels were estimated (acetylcholinesterase, malondialdehyde, Superoxide dismutase) to determine the nootropic activity. The outcome of current research suggest that methanolic extract of A. marmelos fruits significantly reversed the scopalamine induced spatial memory deficits and also inhibits the changed levels of biomarker enzymes due to scopalamine. In conclusion, the separation of the bioactive compounds from A. marmelos fruits can be used as an adjuvant medicine along with allopathic medicine in the treatment of cognitive disorders.

Keywords: Aegle marmelos, Fruits, Amnesia, Biomarker enzymes

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M, K., Murty NVSM, V., & Sastry V, G. (2018). Study on Nootropic activity of Aegle marmelos L fruits. Journal of Integral Sciences, 1(1), 7-11. Retrieved from http://jisciences.com/index.php/journal/article/view/5
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Research Article(s)